Designed to smooth and refine fine lines and superficial wrinkles.

Macdermol® Fine Lines is a soft filler indicated for patients seeking to correct superficial facial skin depressions, including crow's feet and fine lines around the mouth.

This dermal filler is formulated with hyaluronic acid of the highest purity, combining non-cross-linked and low chemically cross-linked HA. Using X-Click technology, it reduces the risk of migration and granuloma formation, ensuring safety and effectiveness.

It integrates smoothly with the skin’s natural structure, providing targeted correction for fine lines and superficial wrinkles.

The technology

Astagen Therapeutics® developed the innovative X-Click technology – a physical cross-linking method that uses no chemical agents, preserving biocompatibility, safety, and the natural properties of HA.

In Macdermol® Fine Lines, X-Click is combined with low chemically cross-linked HA to create a dual cross-linking system.

This approach enhances gel durability, ensures excellent tissue integration, provides a refined appearance, and significantly reduces the risk of migration and granuloma formation.

  • Protected from structural damages thanks to an optimized sterilization process, the HA in MACDERMOL® FINE LINES has an optimal average size in terms of beneficial effects on the extracellular matrix. 

  • Clinical data indicate thatMACDERMOL® FINE LINES has a lower rate of adverse events in comparison with other competitors.

Technical Informations

••• COMPOSITION: Non-animal hyaluronic acid.

••• HA CONCENTRATION: 20 mg/ml

••• HA MOLECULAR WEIGHT: Between 3 and 4 millions Dalton

••• CROSS-LINKING: X-Click Technology + Low BDDE:

••• CROSS-RATE: ●●○○○

••• INDICATION: Corrects fine lines and superficial wrinkles.

••• NEEDLE DIAMETER: 27 G

••• DURATION OF EFFECT: 6 months ¹     

••• ADMINISTRATION: Linear threading technique into the mid dermis.

••• PACKAGING: 1ml prefilled syringe.

¹ Average duration depending on several factors such as patient's skin quality, patient's lifestyle, injection technique of the practitioner, and volume injected.