MACDERMOL® BIOREVITALISATION is particularly indicated to treat photo-aged skin and to correct the loss of glow due to pollution, smoke, stress, alcohol, lack of sleep, nutritional deficiencies or hormonal change.

Multi-bolus technique (0.05 ml per bolus) into the deep dermis and/or subcutaneous tissue, about 1 cm apart, with 27G or 30G needle, or by linear threading technique with a cannula in the face and back of hands.

MACDERMOL® BIOREVITALISATION can be regularly injected without any risk of long-term or delayed adverse events which can occur with repetitive injections of dermal fillers. 

* A topical, needle-free version, classified as sterile cosmetic, is also available on demand. This version is administered through microneedling technique, needleless delivery systems (iontophoresis, ultrasonophoresis, electroporation, etc.) or percutaneously after stratum corneum removal by laser or dermabrasion.

MACDERMOL® BIOREVITALISATION is composed of a high concentration of HA and a revitalizing complex containing alpha-lipoic acid and B vitamins. 

​The HA will stimulate the production of the extracellular components including collagen, elastin and HA. 

​The revitalisation complex will provides a powerful free radical neutralisation by increasing the levels of intracellular glutathione, the body's major antioxidant. 

Glutathione is critically important for detoxifying an array of toxic substances and free radical-generating molecules. It thereby exerts a profound protective effect on cells. 

​Frequently depleted in patients with stress and aging, the levels of this powerful antioxidant will be replenished thus decreasing oxidative stress and cellular damage.