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AN EFFECTIVE
ANTI-CELLULITE TREATMENT

 

Stimulates lipolysis and reduces the 
appearance of 
cellulite
.

MACDERMOL® BIOSLIM is an injectable gel  that corrects localised fat deposits and improves the appearance of gynoid lipodystrophy (cellulite).

MACDERMOL® BIOSLIM is composed of a high concentration of hyaluronic acid (HA) and an anti-cellulite complex of caffeine, pyridoxine. 

WHAT IS CELLULITE ?

Cellulite is a lipodystrophy, i.e. a dystrophy of the subcutaneous fat tissue, and more specifically a superficial hyper lipodystrophy, i.e. an augmentation of the volume and/or the number of the adipocytes located in the superficial subcutaneous tissue.

The cellulite fat is distinguishable from the other hyper lipodystrophies by the fact that it is compacted by a pericellular fibrosis around adipocytes and associated to a phenomenon of water retention.

Visually, it is characterised by the formation of dimples on the skin, especially on the tight, hips and buttocks.

WHY DO WE HAVE CELLULITE ?

There are three factors responsible for the creation of cellulite:

- Adipose tissue augmentation

An imbalance between lipogenesis and lipolysis due to genetic, age-related decrease in hormones, lack of physical activity, over-nutrition (too much calories) or bad nutrition (too much high-glycemic index carbohydrates) leads to an augmentation of the number and/or size of the adipocytes.

- Pericellular fibrosis

Due to hyperglycemia subsequent to carbohydrate ingestion, a glycation process will modify the collagen and will lead to a pericellular fibrosis.

- Water retention

Because of bad venous return, lymphatic insufficiency or alteration of capillary permeability, water stands in the adipose tissue around adipocytes.  

HOW DOES MACDERMOL® BIOSLIM WORK ? 

It will act on the three causes of cellulite:

- Adipose tissue augmentation

Caffeine will stimulate lipolysis and inhibit lipogenesis by stopping triglyceride synthesis while HA will help the hydrolysis of adipocytes. 

- Pericellular fibrosis

Pyrodixine will inhibit the glycation process and HA will restore the collagen.

- Water retention

Arginine will improve blood circulation and HA will absorb and facilitate the elimination of water. 

Besides, HA will also act on the dimpling appearance by filling and smoothing the skin depressions and will improve the aesthetic appearance of the cutaneous irregularities (dimples) due to cellulite. 

HOW MACDERMOL® BIOSLIM IS ADMINISTERED ? 

It is injected by depot technique into the subcutaneous layer on the areas to be treated (upper thighs, hips, buttocks, abdomen, upper arms, internal face of the knees).

Injection of about 0.2 ml at 1 to 2 cm intervals. 

The total injection volume is dependent upon the area to be treated.

CLINICAL RESULTS 

93% of treated women with Nurnberger-Muller Scale III-IV upper thigh cellulite showed evidence of clinical improvement.

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TECHNICAL INFORMATIONS

MACDERMOL® BIOSLIM

••• COMPOSITION:  Non animal HA, Arginine, Pyridoxine, Caffeine,

                                      Zinc, Sodium chloride.  

••• HA CONCENTRATION:    15 mg/ml

                                                                                                                         

••• CROSS-LINKING:    X-Click Technology  

••• EFFECT:   Stimulates lipolysis and reduces the appearance of cellulite.

••• INJECTION ZONES:  Upper thighs, hips, buttocks, abdomen, upper arms,

                                             internal face of the knees.

••• NEEDLE DIAMETER:    30 G

••• TREATMENT REGIMEN:   2 initial sessions 3 weeks. apart, an additional session 2 months after, and then a maintenance session approximately every 6 months.

••• PACKAGING:     1 or 3 ml prefilled syringe     

••• SECONDARY PACKAGING: Sterilised medical grade blister in carton box    

••• STORAGE:   Between +2°C and +25°C    

••• SHELF LIFE:    3 years   

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